LIN Ting1, LI Chang-yu1, ZHANG Jiang-hua2, et al. Anti-inflammatory and Analgesic Efects of Qishen Jiangu Granule[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 151-153.
LIN Ting1, LI Chang-yu1, ZHANG Jiang-hua2, et al. Anti-inflammatory and Analgesic Efects of Qishen Jiangu Granule[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 151-153. DOI: 10.13422/j.cnki.syfjx.2011.04.051.
Objective:To study the anti-inflammatory and analgesic effects of Qishen Jiangu Granule.Method: Models of xylene-induced mice ear edema
albumin-induced rats paw edema were performed to study the anti-inflammatory effect.Acetic acid-induced writhing and hot-plate test in mice were used to study the analgeic effect.Result: The inhibitory rates of low
medium and high dose of Qishen Jiangu Granule on mice ear edema were 13%
12%
and 16% respectively.Albumin-induced rat paw edema were significantly suppressed by Qishen Jiangu Granule(the medium dose was the optimum one).The writhing time of mice induced by hot plate and acetic acid-induced writhing were remarkably improved in a dose-dependent manner.(The inhibitory rate of which were 18%
39%
93%
73% and 12%
25%
48%
79%).Conclusion: Qishen Jiangu Granule has obvious anti-inflammatory and pain-relieving effect.