XU Zhi-lian, LU Hong. Advanced in Research on Nephrotoxicity of Injection[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 261-264.
XU Zhi-lian, LU Hong. Advanced in Research on Nephrotoxicity of Injection[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 261-264. DOI: 10.13422/j.cnki.syfjx.2011.05.028.
药物注射剂肾毒性研究进展
摘要
注射剂以快速、高效等作用特点在临床上发挥着举足轻重的作用
但相应的各种不良反应也逐渐发生。文章列举了注射剂及其产生的肾毒性
并分析了引起肾毒性的原因
将细胞培养技术、蛋白质组学技术在注射剂肾毒性研究中的应用进行归纳总结
展望各技术在药物毒性研究中的应用前景。
Abstract
Injection has been playing a significant role in clinical treatment for the rapid and high-efficiency effects
which also leads to various adverse effects gradually.This assay enumerated nephrotoxicity of injection and analyzed the reasons
and then summarized applications of proteomics and cell culture in researching nephrotoxicity of injection
finally
made some points about prospects for these techniques on the studies of drug toxicity.