LI Nan1, FAN Ying1, JIA Xu-ming1, et al. Effect of Astragali Radix Active Ingredients on Serum Insulin and Adiponectin in Diabetes Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 144-146.
LI Nan1, FAN Ying1, JIA Xu-ming1, et al. Effect of Astragali Radix Active Ingredients on Serum Insulin and Adiponectin in Diabetes Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(5): 144-146. DOI: 10.13422/j.cnki.syfjx.2011.05.066.
Objective:This study was designed to evaluate the effect of three active ingredients of Astragali Radix
namely a Astragalus flavonoids
polysaccharides
and astragalosides
on blood glucose
serum insulin and adi-ponectin in diabetes rats.Method:Diabetes rats were induced by STZ(52 mg.kg-1
peritioneal injection).The rats were grouped for administrating with astragalus flavonoids
polysaccharides
and astragalosides accordingly for 4 weeks
then detection of blood glucose and ELISA assay of serum insulin and adiponectin were done.Result:The blood glucose of diabetes rats ascended(P < 0.05)
serum insulin and adiponectin descended(P < 0.05)
all of these changes were antagonised in various degrees by astragalus flavonoids
polysaccharides and astragalosides
spe-cially
the effect of astragalus flavonoids was obvious(P < 0.05).Conclusion:The three active ingredients of Astrag-alus Radix could influence the content of blood glucose