Objective:To study the relation between cerebral ischemia and Bcl-2（B cell lymphoma/leuke-mia-2

Bcl-2） and the effect of electroacupuncture and total flavones of Acanthopanacis Senticosi Folium for treat-ment.Method:Male Wistar rat model of cerebral ischemia was established with the method of thread middle cerebral artery occlusion.The rats were randomly divided into 6 groups:model control group（group A）

acupuncture treat-ment group（group B）

total flavones group（group C）

acupuncture and Chinese medicine group（group D）

sham operation group（group E）and normal control group（group F）.The neurological deficit score was evaluated and im-munohistochemistry was used to observe the expressions of Bcl-2.Result:Compared with those of the model group

the neurological deficit scores were significantly decreased in the treatment group（P < 0.01

P < 0.05）.The expres-sion of Bcl-2 increased markedly in the A

B

C and D groups（P < 0.01）.Compared treatment of acupuncture with Chinese medicine

group D was more obvious（P < 0.01

P < 0.05）.Conclusion:Electroacupuncture and total fla-vones of Acanthopanacis Senticosi Folium both can increase the expression of Bcl-2 and diminish apoptosis inducedby ischemic cerebra

and electroacupuncture combined with Chinese medicine has significant effect.