Objective:The macroporous adsorptive resins chromatotraphic column combining with polyamide chromatographic column was used to separate the flavonoides

iridoid glycosides and maximum polarity ingredients in industrialization.Method: The flavonoides

iridoid glycosides and maximum polarity ingredients were separated and enriched by CCPP serial laminar analysis equipment

the content of total iridoid glycosides was assayed by the first derivative spectrophotometry;the content of shanzhiside methylester and 8-O-acetyl shanzhiside methylester was determined by HPLC and the change of total iridoid glycosides was investigated in different elution requirement.Result: 70% alcohol was used as dissolvent.Using the ’introduction from inferior surface’ sample introduction mode and ’introduction from superior surface’ eluting mode in the macroporous adsorptive resins

the yield was 20.80%

transfusion ratio for shanzhiside methylester and 8-O-acetyl shanzhiside methylester was 70.77% 73.36% and 68.74% respectively.Conclusion: This production technology may transform experimental achievement to industrial production successfully.