三拗汤制剂水提工艺优选

宋伟

doi:10.13422/j.cnki.syfjx.2011.13.032

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三拗汤制剂水提工艺优选

工艺与制剂 | 更新时间：2024-09-23

- 三拗汤制剂水提工艺优选
- Study on Extracting Technology of Chinese Sanaotang Preparation by Orthogonal Design
- 中国实验方剂学杂志 2011年17卷第13期页码：48-50
- 作者机构：
  
  贵州师范大学
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.13.032
  中图分类号： R283.6
- 纸质出版日期：2011
- 稿件说明：
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[1]宋伟.三拗汤制剂水提工艺优选[J].中国实验方剂学杂志,2011,17(13):48-50.

SONG Wei. Study on Extracting Technology of Chinese Sanaotang Preparation by Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 48-50.
[1]宋伟.三拗汤制剂水提工艺优选[J].中国实验方剂学杂志,2011,17(13):48-50. DOI： 10.13422/j.cnki.syfjx.2011.13.032.

SONG Wei. Study on Extracting Technology of Chinese Sanaotang Preparation by Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 48-50. DOI： 10.13422/j.cnki.syfjx.2011.13.032.

摘要

目的:对中药三拗汤制剂水提工艺进行优化。方法:采用L9（34）正交设计

以盐酸麻黄碱含量和出膏率为考察指标

考察加水量、提取时间、提取次数3个因素对提取的影响。结果:最佳提取工艺为加10倍量的水煎煮1.5 h

再加10倍量的水煎煮2次

每次1 h。结论:工艺经实验重现性好

对进一步的工艺开发有较好的参考价值。

Abstract

Objective:To optimize the water extraction technology of the Chinese Sanaotang Preparation.Method:The water extraction technology optimized by orthogonal design L9（34）

while ephedrine hydrochloride content and the rate of paste as indexes.Factors of water quantity

extraction time and extracting frequency were evaluated for their effects on extraction process.Result:The best water extraction technology was that 10 times of water decocting 1.5 hours

then 10 times of water decocting 2 times

with 1 hour for each time.Conclusion:This technology is stable

practical and worthy of a trial in pharmaceutical production.

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