LI Jin1, HUANG Xue-kuan1, REN Ling-yan2, et al. Effects of Zhaqi Jiangtang Decoction on Blood Glucose and Oxidative Stress in Diabetic Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 124-126.
LI Jin1, HUANG Xue-kuan1, REN Ling-yan2, et al. Effects of Zhaqi Jiangtang Decoction on Blood Glucose and Oxidative Stress in Diabetic Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(13): 124-126. DOI: 10.13422/j.cnki.syfjx.2011.13.055.
Objective:To investigate the effects of Zhaqi Jiangtang Decoction on blood glucose and oxidative stress in diabetic rats.Method:The mode1 rats of diabetes were made by injection STZ into the abdominal cavity.After the model formed
the rats with diabetes were treated with Zhaqi Jiangtang Decoction
Youjiangtang through gastric feeding.The treatment lasted for 4 weeks
the influence on fasting blood glucose(FBG)
superoxide dismutase(SOD)
catalase(CAT)maleicdialdehyde(MDA)for treated rats with diabetes was observed.Result: The levels of FBG and SOD were increased significantly
and the levels of CAT and SOD reduced significantly in the blood serum of the model rats compared to the normal group(P<0.05);Zhaqi Jiangtang Decoction could not only reduce the 1evers of FBG and MDA
but also rise the 1evels of CAT and SOD in the model rats(P<0.05).Conclusion:Zhaqi Jiangtang Decoction has obvious effect to reduce the blood glucose and its mechanism may be related to inhibition of oxidative stress in diabetic rats.