Objective:To obtain the extraction technique of mixed volatile oil from Acorus tatarinowii and Alpinia oxyphlla in Dihuang Yizhi granules and their β-CD inclusion technology.Method:The orthogonal design was applied.The yield of volatile oil was used to evaluate the extraction process by steam distillation method.The inclusion yield and volatile oil inclusion rate were used to determine the inclusion process.Result:The optimized extraction progress parameters were as follows:water volume was 10-fold

extracted time was eight hours

and soaking time was 0.5 h.The optimized inclusion progress parameters were as follows:the rate of oil:β-CD（g:mL） was 1:4

water volume was 1.5-fold

and grinding time was 60 minutes.Conclusion:The yield rate of volatile oil is greater than 1.5% and volatile oil inclusion rate is more than 95%.The optimum extraction process and inclusion process were simple and practicable

which can effectively retain the volatile oil in Dihuang Yizhi granules.