Objective:To investigate the influences of compatibility of Magnoliae Officinalis Cortex with Aurantii Frutus Immaturus on gastric motility in rat.Method:The gastric motility disorder in SD rats was established by injecting L-Arg intraperitoneally for six days

then the rats were given the extract of Magnolia（Magnoliae Officinalis Cortex 10 g·kg-1） by intragastric administration

the compatibility of extract of Magnoliae Officinalis Cortex with Frutus auranti（Magnoliae Officinalis Cortex and Aurantii Frutus Immaturus 20 g·kg-1） by intragastric administration

cisapride（0.004 2 g·kg-1） by intraperitoneal injection

respectively.The improvement in gastric function was observed.Result:Gastrointestinal motility in rats injected with L-Arg intraperitoneally was slowed down

plasma motilin was reduced.The extract of Magnoliae Officinalis Cortex

Magnoliae Officinalis Cortex compatibility with Aurantii Frutus Immaturus could effectively inhibit the decrease in gastrointestinal motility（P<0.05） and plasma motilin（P<0.05）.and there was significant difference between the group Magnoliae Officinalis Cortex and the group Magnoliae Officinalis Cortex compatibility with Aurantii Frutus Immaturus（P<0.05） and there was no significant difference between Magnoliae Officinalis Cortex and the positive drug cisapride.There were significant differences between the group Magnoliae Officinalis Cortex compatibility with Aurantii Frutus Immaturus compared with the group Magnoliae Officinalis Cortex

and the group of compatibility compared with cisapride（P<0.05）.Gastric residual rate in rats given the extract of Magnoliae Officinalis Cortex

the extract of Magnoliae Officinalis Cortex compatibility with Frutus auranti

cisapride were（69.3±13.7）%

（60.7±12.9）% and（70.1±12.9）% respectively;plasma motilin were（85.4±11.2）

（93.1±10.4） and（86.3±12.4）nmol·L-1 accordingly.Gastric residual rate was lower（P<0.05） and plasma motilin was higher（P<0.05） for the decoction duration of 90 min compared with those of duration 60 min or 30 min.Gastric residual rate for the decoction duration 90

60

30 min were（47.7±12.8）%

（59.8±12.1）% and（62.7±11.8）% respectively;plasma motilin were（102.3±10.6）

（92.9±10.1） and（89.6±11.2） nmol·L-1 respectively.Conclusion:The extract of Magnoliae Officinalis Cortex

Magnoliae Officinalis Cortex compatibility with Aurantii Frutus Immaturus can effectively improve the gastric motility disorder in rats

and Magnoliae Officinalis Cortex compatibility with Aurantii Frutus Immaturus is better than Magnoliae Officinalis Cortex alone.The recommended decoction duration is 90 min.