Objective:To evaluate the effects of Shaofu Zhuyu decoction

the decoction minus Wenli herb pair（herbs of warm channel and expelling cold） on hemorheological parameters in rat mode of acute blood stasis

and the influence on platelet aggregation and clotting time in vitro.Method:Rat model of acute blood stasis was used to evaluate the changes in hemorheological parameters

the function of blood coagulation and ovarian.The platelet aggregation was tested with Born’s method.The clotting parameters

including thrombin time（TT）

prothrombin time（PT） and activated partial thromboplastin time（APTT） in vitro

were established.Result:Shaofu Zhuyu decoction showed significant improvements in the hemorheological parameters

including whole blood viscosity and ESR（P<0.05） compared with the model of blood stasis.Meanwhile

the result of vitro assay showed that Shaofu Zhuyu decoction had significantly inhibitory effects on the platelet aggregation and prolonged clotting time for TT

PT and APTT.The effects of the decoction minus Wenli herb pair only showed effect of reducing plasma viscosity and extending TT and PT.Conclusion:Shaofu Zhuyu decoction could improve the indexes of hemorheology in rat model of blood stasis

and showed significant inhibitory effect on platelet aggregation and clotting time.Furthermore

Wenli herbs play an important role in the biological effect for the whole prescription.