CHEN Jin-xin1, LI Yun-xiang2, WANG An-guo2, et al. Expression of Nerve Growth Factor in Rats Model of Chronic Prostatitis Treated with Qianlieshutong Capsules[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(15): 224-226.
CHEN Jin-xin1, LI Yun-xiang2, WANG An-guo2, et al. Expression of Nerve Growth Factor in Rats Model of Chronic Prostatitis Treated with Qianlieshutong Capsules[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(15): 224-226. DOI: 10.13422/j.cnki.syfjx.2011.15.076.
Objective:To detect the expression of nerve growth factor(NGF) in glandula prostata of chronic prostatitis(CP) rat model treated with Qianlie Shutong capsule.Method:The specific primers and probes for Taqman real-time PCR was disigned according to the NGF and GAPDH cDNA sequence.The expression level of NGF as measured by relative quantification real-time PCR in rat model treated with Qianlie Shutong capsule 0.84
0.42
0.21 g·kg-1
ig for 30 days.Result:Treatment with Qianlieshutong decreased the expression of NGF in glandula prostata of rat model with CP significantly compared to the control group.Conclusion:The expression levels of NGF was degraded in CP rat model treated with Qianlieshutong.