Objective:To prove Gongdiwan’s function of improving immune system

and inhibiting bacterium through pharmacodynamics study.Method:①Study on Gongdiwan’s function of inhibiting bacterium in vitro through slotted method;②Study on Gongdiwan’s influence to mice’s function of Carbon clearance:select 50 ICR mice

male

which were randomized to control group

Liuwei Dihuang group（dosage:2 gram crude drug per kilogram）

Gongdiwan high dosage

mild dosage and low dosage group（18 grams crude drug per kilogram

9 grams crude drug per kilogram

4.5 grams crude drug per kilogram）.③Gongdiwan’s influence on normal mice’s delayed type hypersensitivity

select 50 ICR mice

male

weighting between 18-22 grams

which were randomized to 5 groups

each group has 10 mice

the grouping method ditto.Result:Gongdiwan had no function of inhibiting staphylococcus aureus and proteus

but it could inhibit beta hemolytic streptococcus and escherichia coil in vitro.The result showed that the inhibiting bacterium function of Gongdiwan was weaker then that of western medicine group.Comparing with control group

Gongdiwan could obviously improve the mice’s function of Carbon clearance

especially when using low dose（P<0.01）

that was to say

Gongdiwan could improve the non-specific immune function of mice.Comparing with control group

the low dose Gongdiwan Group could obviously enhance the DNCB induced mice’s delayed type hypersensitivity（P<0.05）.Conclusion:Gongdiwan can inhibit bacterium and improve the function of immune system.Therefore

it can effectively treat urinary tract infection（stranguria caused by overstrain） that belong to spleen and kidney yang deficiency syndrome

which are difficult to be cured by western medicine.Thus

Gongdiwan can treat the catabasis of chronic urinary tract infection.