Objective:To study the cellular growth of cell suspension culture and kinetics of product accumulation in Siraitia grosvenorii

and provide a theoretical basis for optimal control in the training process.Method:The fresh weight

dry weight and the contents of mogroside were investigated in a cell cycle

the growth curve and growth rate curves were drawn.Result:The growth cycle of S.grosvenorii cell suspension culture was 21 days

the lag phase was 0-6 d

the log phase was 7-21 d

there was transient stability in the stable phase

the decline phase achieved on the 22th day.The highest fresh weight and dry weight were achieved on the 21th day

and reached 693.0

416.0 g·L-1respectively

the maximum growth rate reached 0.040 g·L-1·d-1.The mogroside and mogroside Ⅴsynthesize rapidly on the 7th day

the highest growth rate of mogroside and mogroside Ⅴ were achieved on the 21th day

and reached 0.032 8

0.054 7 g·L-1·d-1 respectively.Conclusion:The combined study of cellular growth and product accumulation can figure out the dynamic changes of product accumulation

and provide a theoretical basis for optimal control in the training process

regulation of metabolism and large-scale industrialization in S.grosvenorii.