大柴胡汤对梗阻性黄疸患者术后血清TBIL,ALT,AST的影响

郑帅; 李忠廉

doi:10.13422/j.cnki.syfjx.2011.23.039

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大柴胡汤对梗阻性黄疸患者术后血清TBIL,ALT,AST的影响

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- 大柴胡汤对梗阻性黄疸患者术后血清TBIL,ALT,AST的影响
- Effects of Dachaihu Tang on Serum Concentration of TBIL,ALT and AST in Post-operative Patients with Obstructive Jaundice Surgery
- 中国实验方剂学杂志 2011年17卷第23期页码：231-233
- 作者机构：
  
  1. 天津医科大学研究生院
  2. 天津市南开医院肝胆外科
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2011.23.039
  中图分类号： R285
- 纸质出版日期：2011
- 稿件说明：
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[1]郑帅,李忠廉.大柴胡汤对梗阻性黄疸患者术后血清TBIL,ALT,AST的影响[J].中国实验方剂学杂志,2011,17(23):231-233.

ZHENG Shuai1, LI Zhong-lian2. Effects of Dachaihu Tang on Serum Concentration of TBIL,ALT and AST in Post-operative Patients with Obstructive Jaundice Surgery[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(23): 231-233.
[1]郑帅,李忠廉.大柴胡汤对梗阻性黄疸患者术后血清TBIL,ALT,AST的影响[J].中国实验方剂学杂志,2011,17(23):231-233. DOI： 10.13422/j.cnki.syfjx.2011.23.039.

ZHENG Shuai1, LI Zhong-lian2. Effects of Dachaihu Tang on Serum Concentration of TBIL,ALT and AST in Post-operative Patients with Obstructive Jaundice Surgery[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(23): 231-233. DOI： 10.13422/j.cnki.syfjx.2011.23.039.

摘要

目的:观察大柴胡汤对梗阻性黄疸患者术后血清总胆红素（total bilirubin

TBIL）、谷丙转氨酶（alanineaminotransferase

ALT）及谷草转氨酶（aspartate aminotransferase

AST）的影响。方法:将手术后的366例梗阻性黄疸患者随机分为治疗组201例、对照组165例。治疗组在对照组治疗的基础上辅以口服大柴胡汤（柴胡30 g

大黄15 g

枳实12 g

黄芩15 g

半夏12 g

芍药15 g

大枣6枚

每日2次

100 mL/次）

从术后第2天开始

连服7 d;对照组行梗阻性黄疸术后常规治疗

观察两组患者术后5～7

12～14 d血清TBIL

ALT及AST变化情况。结果:两组患者手术后血清TBIL

ALT及AST水平均明显下降

与手术前相比差异有统计学意义（P<0.05）;治疗组血清TBIL

ALT及AST降低明显

与对照组相比差异有统计学意义（P<0.05）。两组手术后5～7 d

12～14 d血清TBIL

ALT

AST

对照组TBIL（138.3±20.4）μmol.L-1

ALT（124.5±17.9）U.L-1

TBIL（128.1±17.9）μmol.L-1

ALT（120.0±17.3）U.L-1

AST（54.5±4.9）U.L-1;治疗组TBIL（132.6±18.7）μmol.L-1

ALT（119.1±17.7）U.L-1

TBIL（121.0±17.2）μmol.L-1

ALT（114.3±17.1）U.L-1

AST（53.1±5.0）U.L-1

两组相比有显著性差异（P<0.05）。结论:大柴胡汤能有效降低梗阻性黄疸患者术后血清TBIL

ALT及AST

起到促进肝脏功能恢复的作用。

Abstract

Objective:To observe the influence of Dachaihu Tang on serum concentration of total bilirubin（TBIL）

alanine aminotransferase（ALT）and aspartate aminotransferase（AST）in Post-operative patients with obstructive jaundice surgery.Method: 366 cases of post-operative patients with obstructive jaundice were randomly divided into treatment group of 201 cases and control group of 165 cases.The control group received conventional treatment after surgery of obstructive jaundice

treatment group was supplemented with high daisaikotofrom the second day after surgery

lasting a total of seven days

the serum concentrations of TBIL

ALT and AST were observed after 5-7 d and 12-14 d in both group.Result:The serum concentrations of TBIL

ALT and AST in both group were significantly decreased compared with pre-operation.Compared with the control group there were statistically significant differences（P<0.05）.The serum concentrations of TBIL

ALT and AST in treatment group decreased significantly

compared with the control group significantly（P<0.05）.Conclusion: Dachaihu Tang can effectively reduce the serum concentration of TBIL

ALT and AST

playing an active role in liver protection.

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