Objective:To observe the effect of Qingchang granule in experimental functional constipation.Method: Qingchang granule low

medium and high（6.5

13

26 g·kg-1·d-1）dose group

Dahuang Tongbian Keli（3.12 g·kg-1·d-1）group

polyethylene glycol PEG 4 000 powder（5.2 g·kg-1·d-1） group.ig every day to medicine

the continuous 5 d.To investigate the role of Qingchang granule in the time and number of defaecation

volume of intestine

propulsive movement of small intestine of the experimental mouse（defaecation experiment

volume of intestine experiment

charcoal powder propulsion experiment）

explore the biological effect of the Qingchang granule in experimental functional Constipation.Result: Dry and water loss model group comparison

Qingchang granule

high dose group of mice

shorten the time required for the first time defecate in row 4 h and black points increased（P<0.01）.And intestinal power obstacles model

Qingchang granule group compared low

medium and high dose group first row black mice and shorten the time and increase in row 4 h black then points（P<0.01

P<0.05）.And blank compared to the Qingchang granule with mice increased defecate time reduced doses

defecate number increased（P<0.01）.And blank compared Qingchang granule low

medium and high quality throughout the obvious increase of the dose group（P<0.05

P<0.01）.Carbon ink distance and promote blank compared increases obviously（P<0.05

P<0.01）.Conclusion:The results indicate that Qingchang granule could promote defecation

decrease the intestine absorbed the moisture

increased volume of intestine

enhanced the enterocinesia and propulsive movement of intestine.