FU Liang1, RAO Xiao-yong2, HUANG Kai2, et al. Extraction of Volatile Oil and Preparation Technology of β-Cyclodextrin Inclusion from Sini Effervescent Tablet[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 5-9.
FU Liang1, RAO Xiao-yong2, HUANG Kai2, et al. Extraction of Volatile Oil and Preparation Technology of β-Cyclodextrin Inclusion from Sini Effervescent Tablet[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 5-9. DOI: 10.13422/j.cnki.syfjx.2012.04.001.
并对包合物进行验证。结果:最佳提取工艺为药材不浸泡、加6倍量水、蒸馏8 h;胶体磨法的最佳包合工艺为挥发油与β-环糊精按(1 mL∶8 g)投料、包合时间45 min
加水量80 mL。结论:胶体磨法包合干姜挥发油
工艺简单、可行
适合工业化大生产。
Abstract
Objective:To study on extraction process of volatile oil from dried ginger and its inclusive compound by β-cyclodextrin(β-CD) from Sini effervescent tablet.Method:Orthogonal test was employed to investigate effect of water volume
soak time and distilled time on extraction of volatile oil;and took comparative test of saturated water solution method
colloid mill method
and ultrasound method
choose optimum inclusion method with inclusion efficiency of volatile oil
yield of inclusion and the content of oil in inclusion as comprehensive indexes;Optimum inclusion technology of colloid mill method was optimized by orthogonal test
and validate inclusion compound.Result:Optimum extraction technology conditions were to add 6 times the amount of water
and distilled 8 h without soaking;Optimum inclusion technology of colloid mill method was as follows:proportion of volatile oil to β-CD was 1∶8(mL∶g)
inclusion time was 45 min;the amount of water was 80 mL.Conclusion:Inclusion technology(colloid mill method)of volatile oil from dried ginger was simple
feasible and appropriated for large-scale production.