SHA Ai-long1, CHEN Hong-ling1, MENG Qing-yan2. Anti-flammatory and Antalgic Effects of Ziziphora clinopodioides and its Acute Toxicity[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 202-204.
SHA Ai-long1, CHEN Hong-ling1, MENG Qing-yan2. Anti-flammatory and Antalgic Effects of Ziziphora clinopodioides and its Acute Toxicity[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(4): 202-204. DOI: 10.13422/j.cnki.syfjx.2012.04.010.
antalgic effects and acute toxicity of Ziziphora clinopodioides Lam.Method:The inhibition of auricle edema induced by xylene and paw edema induced by formaldehyde were used to test the anti-inflammation
pain caused by acetic acid in mice was used to evaluate the antalgic effect.Oral administration was used for acute toxicity tests.Result:Z.clinopodioides of low
medium and high dose groups on xylene in rats induced by Auricular swelling
foot swelling in mice induced by formaldehyde and acetic acid twisting had a significant inhibition in mice induced(P<0.05).All mouse were survived
and no toxic reaction was found in the observed period.Conclusion:Z.clinopodioides has obvious anti-inflammatory and antalgic effects.The clinical dosage of the tablets is within the safty range.