To analyze the correlations between hepatotoxicity and four properties

five tastes

meridian entry of Chinese materia medica.Chinese herbs with hepatotoxicity were regarded as the research objects

which were collected from published reports and monographs.The property theory of Chinese materia medica were referred to<Dictionary of Chinese Materia Medica>.The regularities of four properties

five tastes

and meridian entry of Chinese herbs with hepatotoxicity

and the correlations between hepatotoxicity and property theory of Chinese materia medica were analyzed.① The differences in terms of four properties of Chinese herbs with hepatotoxicity or general Chinese herbs were obvious（P<0.05）

and the order from high to low was cold

warm

neutral

cool and hot

which was similar between two kinds of Chinese herbs.There was no correlation between hepatotoxicity and four properties;②The difference in terms of five tastes of Chinese herbs with hepatotoxicity was obvious（P<0.05）

and the order from high to low was bitter

acrid

sweet

sour

astringent

salty and bland.The difference in terms of five tastes of of general Chinese herbs was also obvious（P<0.05）

and the order from high to low was bitter

sweet

acrid

salty

astringent

sour and bland.There existed some correlation between hepatotoxicity and five tastes（P<0.05

rp=0.137）;③The differences in terms of meridian entry of Chinese herbs with hepatotoxicity or general Chinese herbs were obvious（P<0.05）

and the order from high to low was liver

lung

stomach

spleen

kidney

heart

large intestine

bladder

gallbladder

small intestine

pericardium and triple energizer meridian

which was similar between two kinds of Chinese herbs.There was no correlation between hepatotoxicity and meridian entry.The differences in terms of four properties

five tastes and meridian entry of Chinese herbs with hepatotoxicity are obvious.Comparied with general Chinese herbs

there is no correlation between hepatotoxicity and four properties or meridian entry

while there is some weak correlation between hepatotoxicity and five tastes.