Objective:To study on optimum forming technology of Zexie dropping pill.Method: With appearance quality

dissolved time

weight difference of dropping pill

orthogonal test was used to optimize ratio of matrix

the content of drug

temperature of liquid

dropping distance and other factors.Result: Optimum forming technology conditions of Zexie dropping pill were as follows: liquid paraffin was refrigerant

the content of drug was 30%

PEG 4000-PEG 6000（1∶3） was optimal matrix ratio

liquid temperature was（85±1） ℃

dropping distance was 2 cm

temperature of refrigerant was（6±0.2） ℃

freeze-pillar height was 70 cm

dropping velocity was 40 drops per minute

internal and external diameter of burette was 1.64 mm and 2.22 mm.Conclusion: Optimized forming technology of Zexie dropping pill was simple and feasible

and suitable for industrial production.