麻黄与老鹳草配伍前后有效成分提出率

薛强强; 许宁宁; 张守元; 杨官娥

doi:10.13422/j.cnki.syfjx.2012.08.013

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麻黄与老鹳草配伍前后有效成分提出率

工艺与制剂 | 更新时间：2024-09-23

- 麻黄与老鹳草配伍前后有效成分提出率
- Extract Rate of Active Ingredient before and after Compatibility of Ephedrae sinica and Erodium stephanianum
- 中国实验方剂学杂志 2012年18卷第8期页码：50-54
- 作者机构：
  
  山西医科大学药学院
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2012.08.013
  中图分类号： TQ461
- 纸质出版日期：2012
- 稿件说明：
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[1]薛强强,许宁宁,张守元,杨官娥.麻黄与老鹳草配伍前后有效成分提出率[J].中国实验方剂学杂志,2012,18(08):50-54.

XUE Qiang-qiang, XU Ning-ning, ZHANG Shou-yuan, et al. Extract Rate of Active Ingredient before and after Compatibility of Ephedrae sinica and Erodium stephanianum[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(8): 50-54.
[1]薛强强,许宁宁,张守元,杨官娥.麻黄与老鹳草配伍前后有效成分提出率[J].中国实验方剂学杂志,2012,18(08):50-54. DOI： 10.13422/j.cnki.syfjx.2012.08.013.

XUE Qiang-qiang, XU Ning-ning, ZHANG Shou-yuan, et al. Extract Rate of Active Ingredient before and after Compatibility of Ephedrae sinica and Erodium stephanianum[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(8): 50-54. DOI： 10.13422/j.cnki.syfjx.2012.08.013.

摘要

目的:考察麻黄与老鹳草配伍前后主要活性成分盐酸麻黄碱和没食子酸提出率的变化

探讨两药配伍使用的增效作用机制。方法:以盐酸麻黄碱和没食子酸为指标

HPLC测定含量

采用正交试验法优选配伍前后提取工艺。结果:麻黄配伍后盐酸麻黄碱的提出率分别为5.136

5.485 mg·g-1

老鹳草配伍前后没食子酸的提出率分别为1.352

1.564 mg·g-1。结论:麻黄和老鹳草配伍前后盐酸麻黄碱、没食子酸提出率均增加

为两药配伍使用增效作用提供依据。

Abstract

Objective:To investigate change of extract rate of main active ingredient before and after compatibility of Ephedrae sinica and Erodium stephanianum

such as ephedrina hydrochloridum and galic acid

and explore synergistic effect mechanism when compatibility of this two medicines.Method: Taking the contents of ephedrina hydrochloridum and galic acid as indexes

before and after compatibility

optimum extraction technology was optimized by orthogonal test and HPLC was adopted to determine the content of each index components.Result: Before and after compatibility

Extract rates of ephedrina hydrochloridum from E.sinica were 5.136

5.485 mg·g-1

extract rates of galic acid from E.stephanianum were 1.352

1.564 mg·g-1.Conclusion: After compatibility of E.sinica and E.Stephanianum

extract rate of ephedrina hydrochloridum and galic acid increased respectively.It provided basis for synergistic effect when two medicines were companied with each other.

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