Objective:To instruct the fingerprint of Armeniacae Semen Amarum

enhance the method of quality control.Method: The separation was performed on an C18 chromatography column

using acetonitrile-0.1% of phosphoric acid as mobile phase

with the flow rate of 1 mL·min-1;the wavelength was set at 225 nm.’TCM chromatographic fingerprint similarity evaluation system（2004A edition）’ recommended by state food and drug administration was used for calculating

to determine the methods of Armeniacae Semen Amarum fingerprint research.Result: Methodology of fingerprint investigation results is qualified;the similarity in 10 batch samples was between 0.5 and 0.9.Conclusion: The characteristics of large difference absorption wavelength of multiple components for effectively improve fingerprint information

Armeniacae Semen Amarum decoction pieces quality control to provide the reference.