Objective:To discuss efficiency of combined treatment of enalapril and tanshinon on acute exacerbation of chronic pulmonary heart disease and evaluate its safety.Method: One hundred and fourteen collected patients with acute exacerbation of chronic pulmonary heart disease in hospital were randomLy divided into two groups

observation group and control group

57 patients in each group.On the basis of conventional clinical therapy

enalapril treatment was given to patients in the control group

the observation group was given tanshinon on base of the treatment in the control group

after treatment

the curative effect in the two groups were assessed

while the indicators of changes in hemorrheology in patients were monitored.Result: The observation group and control group response rate were 90.7% and 80.7%

respectively

the rate in the observation group were significantly higher than that in control group（P<0.05）.Before and after treatment inindicators of blood gas

blood flow and cardiac function and others were different（P<0.05） in two groups

while after treatment in observation group

the indicators were significantly better than that in control group（P<0.05）;adverse reactions between the two groups had no significantly difference.Conclusion: The curative effect of combined treatment of enalapril and tanshinon medicine is significant better

and the treatment is safe.The combined application of enalapril and tanshinon should be widely recommend.