ZHAO Yu-wei1, YU Miao1, HE Li2, et al. Optimization of Extraction Process for Zidianling Granule[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 32-35.
ZHAO Yu-wei1, YU Miao1, HE Li2, et al. Optimization of Extraction Process for Zidianling Granule[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 32-35. DOI: 10.13422/j.cnki.syfjx.2012.09.006.
Objective:To optimize extraction technology of Zidianling granule.Method:With baicalin and matrine as indicators
main factors of extraction process were optimized by L9(34)orthogonal test
the content of baicalin and matrine were determined by HPLC.Result:Optimum extraction process was determined as follows: Scutellaria baicalensis and other five herbs was extracted 2 times with 6 times the amount of 70% ethanol
1 hour each time;Residues of above mentioned drugs and the others herbs(Bubalus bubalis and the others herbs) were extracted 3 times with 10 times the amount of wate
1.5 h each time.Conclusion:This optimized technology for Zidianling granules was economic