ZHANG Zhi-wei1, HAI Li-na1, GAO Zhi-yuan1, et al. Study on Rationality for Compatibility of Kushen Injection[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 229-232.
ZHANG Zhi-wei1, HAI Li-na1, GAO Zhi-yuan1, et al. Study on Rationality for Compatibility of Kushen Injection[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 229-232. DOI: 10.13422/j.cnki.syfjx.2012.09.047.
Objective:To study the rationality for compatibility of Kushen and Baituling.Method: Four mouse models of tumor
pain
hemorrhage and inflammation were used to evaluate the pharmacodynamic effects of Compound Kushen injection(15.75
3.75 g·kg-1)
Kushen injection(10.5
5.25
2.63 g·kg-1)and Baituling injection(4.5
2.25
1.13 g·kg-1).Result: Compound Kushen injection and Kushen injection showed significant anti-tumor effect(high and middle doses)
analgesia(high and middle doses)
anti-inflammation(high dose)and hemostasis(high dose) effects.Baituling injection showed effects on analgesia(high and middle doses) and hemostasis(high dose).Compound Kushen injection could enhance the anti-tumor effect and anti-inflammation(three doses) of Kushen
promote the action of analgesia for strengthen and duration
shorten the coagulation time and hemorrhage time(high dose).Conclusion: Kushen and Baituling have synergistic action with compatible rationality in Compound Kushen injection.