寒水石生品、炮制品在人工胃肠液中的溶出率

陆景坤; 陈朝军; 周昊菲; 刘智杰; 毅和

doi:10.13422/j.cnki.syfjx.2012.09.060

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寒水石生品、炮制品在人工胃肠液中的溶出率

工艺与制剂 | 更新时间：2024-09-23

- 寒水石生品、炮制品在人工胃肠液中的溶出率
- Dissolution Rate of Raw and Processed Products of Gypsum Calcite in Artificial Intestinal Fluid and Gastric Juice
- 中国实验方剂学杂志 2012年18卷第9期页码：23-25
- 作者机构：
  
  内蒙古医学院药学院
- 作者简介：
- 基金信息：
  
  内蒙古自治区教育厅高等学校科学研究项目（NJ09110）
- DOI：10.13422/j.cnki.syfjx.2012.09.060
  中图分类号： R283.6
- 纸质出版日期：2012
- 稿件说明：
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[1]陆景坤,陈朝军,周昊菲,刘智杰,毅和.寒水石生品、炮制品在人工胃肠液中的溶出率[J].中国实验方剂学杂志,2012,18(09):23-25.

LU Jing-kun, CHEN Zhao-jun, ZHOU Hao-fei, et al. Dissolution Rate of Raw and Processed Products of Gypsum Calcite in Artificial Intestinal Fluid and Gastric Juice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 23-25.
[1]陆景坤,陈朝军,周昊菲,刘智杰,毅和.寒水石生品、炮制品在人工胃肠液中的溶出率[J].中国实验方剂学杂志,2012,18(09):23-25. DOI： 10.13422/j.cnki.syfjx.2012.09.060.

LU Jing-kun, CHEN Zhao-jun, ZHOU Hao-fei, et al. Dissolution Rate of Raw and Processed Products of Gypsum Calcite in Artificial Intestinal Fluid and Gastric Juice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 23-25. DOI： 10.13422/j.cnki.syfjx.2012.09.060.

摘要

目的:对南、北寒水石奶淬、水淬、生品在人工胃肠液中溶出率进行分析。方法:通过人工模拟胃肠环境来分析寒水石的溶出情况

利用配位滴定法检测样品中主成分钙含量

计算溶出率。结果:南、北寒水石在人工胃液中溶出率在70%～110%

溶出率依次为奶淬<水淬<生品;在人工肠液中

南寒水石溶出率低于10%

其中生品溶出率最低

北寒水石低于20%

水淬制品溶出率最低。结论:南、北寒水石可能主要在胃内吸收

肠内吸收较少。

Abstract

Objective:To analyze dissolution ratio of milk quenching product

water quenching product and raw materials of Gypsum and Calcite in artificial intestinal fluid and gastric juice.Method:Dissolution rate of Calcium were analyzed in artificial gastrointestinal environment

to calculate dissolution ratio with detected the content of principal component（calcium） by coordination titration.Result:Dissolution ratio of Gypsum and Calcite in artificial gastric juice were between 70% and 110%

order of dissolution rate were:milk quenching<water quenching<raw materials.In artificial intestinal fluid

dissolution rate of Calcite was less than 10%

dissolution ratio of raw materials was the lowest

while dissolution rate of Gypsum was less than 20%

the lowest one was water quenching products.Conclusion:Gypsum and Calcite might be mainly absorbed in stomach

and it was lower in the intestinal.

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