不同厂家黄连上清片质量比较

王胤; 沈力; 周浓; 刘氏清水

doi:10.13422/j.cnki.syfjx.2012.09.077

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不同厂家黄连上清片质量比较

化学与分析 | 更新时间：2024-09-23

- 不同厂家黄连上清片质量比较
- Acomparative Research on Quality of Huanglian Shangqing Tablets from Different Manufacturers
- 中国实验方剂学杂志 2012年18卷第9期页码：99-103
- 作者机构：
  
  1. 大理学院药学院
  2. 重庆三峡医药高等专科学校中药研究所
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2012.09.077
  中图分类号： R286.0
- 纸质出版日期：2012
- 稿件说明：
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[1]王胤,沈力,周浓,刘氏清水.不同厂家黄连上清片质量比较[J].中国实验方剂学杂志,2012,18(09):99-103.

WANG Yin1, SHEN Li2, ZHOU Nong1, et al. Acomparative Research on Quality of Huanglian Shangqing Tablets from Different Manufacturers[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 99-103.
[1]王胤,沈力,周浓,刘氏清水.不同厂家黄连上清片质量比较[J].中国实验方剂学杂志,2012,18(09):99-103. DOI： 10.13422/j.cnki.syfjx.2012.09.077.

WANG Yin1, SHEN Li2, ZHOU Nong1, et al. Acomparative Research on Quality of Huanglian Shangqing Tablets from Different Manufacturers[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(9): 99-103. DOI： 10.13422/j.cnki.syfjx.2012.09.077.

摘要

目的:研究不同厂家黄连上清片的质量情况以及对问题的分析

为提高药品标准

正确地评价药品质量提供理论依据。方法:通过对7家生产厂家10批样品进行片芯质量测定

样品粉末显微镜观察

建立5种蒽醌类化合物（芦荟大黄素、大黄酸、大黄素、大黄酚和大黄素甲醚）含量测定方法

并对样品中5种蒽醌类化合物的含量进行测定并比较。结果:不同生产厂家的产品显微观察无区别

但片重差异和5种蒽醌类化合物存在较大差异。结论:不同厂家的黄连上清片由于制剂工艺、原材料质量等不同

导致了产品质量存在较大差异。

Abstract

Objective: To improve the drug standard and provide a theoretical basis for the correct evaluation of the quality of the drugs

the qualities of Huanglian Shangqing tablets from different manufactures were investigated and some problems were analyzed.Method: The core tablets of 10 batches from 7 manufacturers were weighed and the powder samples were microscopically observed.Method for determination of 5 kinds of anthraquinone（aloe-emodin

rhein

emodin

chrysophanol and physcion） was established and the content of anthraquinone was assayed.Result: There are no microscopic indifferences exist among different tablets

while the weight of the tablets as well as the content five kinds of anthraquinone was quite different.Conclusion: Big differences of the quality of the products exist among different products

which may result from different raw materials and preparation process.

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