Objective: To observe the Simiao Yongan decoction on qi stagnancy and blood stasis syndrome in patients with chronic heart failure and to explore the related mechanism.Method: Cases of stagnancy of Qi and blood stasis with chronic heart failure were randomly divided into the observation group

the control group

with 30 cases in each group.Two groups of patients were given aspirin enteric-coated tablets

oral

100 mg daily;atorvastatin tablets

oral

20 mg daily.In the observation group based on the treatment of control group given Simiao Yongan decoction.The two groups were daily 4 weeks as 1 course.An interval of 1 week

was scheduled before starting second course.The total treatment lasted 4 courses.Result: The clinical cure rate was observed in observation group 57.50%

control group 40%（P<0.05）.The total efficiency of the observation group was 95%

control group 75%（P<0.05）.After treatment of high shear viscosity of whole blood

blood middle shear viscosity

blood low shear viscosity

plasma viscosity

hematocrit in observation group were（3.52±0.62）

（4.33±0.54）

（7.18±1.55）

（1.32±0.14）mPa·s

（34.43±5.54）%

compared to the control group respectively（3.72±0.58）

（4.52±0.64）

（7.41±1.23）

（1.41±0.15）mPa·s

（36.78±5.68）%

（P<0.05）.After treatment

the observation group was better than the control group（P<0.05）.TC

TG

LDL-C

HDL-C group respectively（3.62±1.60）

（2.32±1.54）

（3.15±1.55）

（1.92±0.14） mmol·L-1

the control group respectively（4.75±1.58）（3.32±1.64）（4.31±1.23）（1.56±0.15） mmol·L-1

（P<0.05）.After treatment

the observation group was better than control group（P<0.05）.Conclusion:Clinical curative effect of Simiao Yongan decoction on qi stagnancy and blood stasis syndrome of chronic heart failure is significant.Its mechanism may be related to effect on hemorheology and blood lipids indicators concerned.