金银花闪式提取工艺优选

王玥; 杜守颖; 吴清; 肖瑶; 王英姿; 林宏英; 戎堃; 袁航

doi:10.13422/j.cnki.syfjx.2012.15.019

您当前的位置：

首页 >

文章列表页 >

金银花闪式提取工艺优选

工艺与制剂 | 更新时间：2024-09-23

- 金银花闪式提取工艺优选
- Optimization of Extraction Technology of Active Ingredients from Lonicera japonica by Flash Extraction
- 中国实验方剂学杂志 2012年18卷第15期页码：18-21
- 作者机构：
  
  北京中医药大学中药学院
- 作者简介：
- 基金信息：
  
  国家自然科学基金面上项目（81073057）;教育部博士点基金项目（20090013110007）;北京中医药大学复方中药制药研究创新团队（2011-CXTD-13）;国家重点实验室开放基金项目（SKL2010Z0304,SKL2010M0302）
- DOI：10.13422/j.cnki.syfjx.2012.15.019
  中图分类号： R284
- 纸质出版日期：2012
- 稿件说明：
移动端阅览
[1]王玥,杜守颖,吴清,肖瑶,王英姿,林宏英,戎堃,袁航.金银花闪式提取工艺优选[J].中国实验方剂学杂志,2012,18(15):18-21.

WANG Yue, DU Shou-ying, WU Qing, et al. Optimization of Extraction Technology of Active Ingredients from Lonicera japonica by Flash Extraction[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 18-21.
[1]王玥,杜守颖,吴清,肖瑶,王英姿,林宏英,戎堃,袁航.金银花闪式提取工艺优选[J].中国实验方剂学杂志,2012,18(15):18-21. DOI： 10.13422/j.cnki.syfjx.2012.15.019.

WANG Yue, DU Shou-ying, WU Qing, et al. Optimization of Extraction Technology of Active Ingredients from Lonicera japonica by Flash Extraction[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 18-21. DOI： 10.13422/j.cnki.syfjx.2012.15.019.

摘要

目的:优选闪式提取金银花中有效成分的工艺条件。方法:以绿原酸、木犀草苷的含量为指标

考察乙醇体积分数、乙醇用量及提取时间等影响因素

采用正交试验设计优选闪式提取工艺

并与文献报道方法相比较。结果:单独以绿原酸为指标时

最佳提取工艺为15倍量40%乙醇闪式提取1.5 min;单独以木犀草苷或综合考虑绿原酸和木犀草苷2个指标时

最佳提取工艺为15倍量60%乙醇闪式提取1 min。结论:优选工艺简单、经济、提取率高

为金银花药材及其制剂中有效成分的快速提取及质量控制提供新思路。

Abstract

Objective: To optimize flash extraction process conditions of active ingredients from Lonicera japonica.Method: With the content of chlorogenic acid and luteoloside as indexes

taking the concentration of ethanol

ethanol dosage and extraction time as factors

flash extraction technology was optimized by orthogonal test

and compared with reported method.Result: When chlorogenic acid alone as index

optimum extraction technology was:flash extracted 1.5 min with 15 times the amount of 40%ethanol;When luteoloside alone as index or comprehensive chlorogenic acid and luteoloside as indexes

optimum extraction technology was:flash extracted 1 min with 15 times the amount of ethanol.Conclusion: This optimized technology was simple and economic with high extraction ratio

it could provide new ideas for rapid extraction and quality control of active ingredients from L.japonica and its preparations.

关键词

Keywords

references

浏览量

373

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

野菊花栓剂质量标准研究

正交试验优选健胃消食口崩片提取工艺

野菊花超声辅助提取工艺优选

暑热宁合剂提取工艺优化