黄连紫草膏中地黄、紫草的醇提工艺优选

刘丽花; 翟来超; 陈天朝

doi:10.13422/j.cnki.syfjx.2012.15.023

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黄连紫草膏中地黄、紫草的醇提工艺优选

工艺与制剂 | 更新时间：2024-09-23

- 黄连紫草膏中地黄、紫草的醇提工艺优选
- Optimization of Ethanol Extraction Technology for Rehmannia glutinosa and Arnebia euchroma from Huanglian Zicao Gel
- 中国实验方剂学杂志 2012年18卷第15期页码：35-38
- 作者机构：
  
  河南中医学院第一附属医院药学部
- 作者简介：
- 基金信息：
  
  河南中医学院院级课题（2008kj14）
- DOI：10.13422/j.cnki.syfjx.2012.15.023
  中图分类号： R286
- 纸质出版日期：2012
- 稿件说明：
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[1]刘丽花,翟来超,陈天朝.黄连紫草膏中地黄、紫草的醇提工艺优选[J].中国实验方剂学杂志,2012,18(15):35-38.

LIU Li-hua, ZHAI Lai-chao, CHEN Tian-chao. Optimization of Ethanol Extraction Technology for Rehmannia glutinosa and Arnebia euchroma from Huanglian Zicao Gel[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 35-38.
[1]刘丽花,翟来超,陈天朝.黄连紫草膏中地黄、紫草的醇提工艺优选[J].中国实验方剂学杂志,2012,18(15):35-38. DOI： 10.13422/j.cnki.syfjx.2012.15.023.

LIU Li-hua, ZHAI Lai-chao, CHEN Tian-chao. Optimization of Ethanol Extraction Technology for Rehmannia glutinosa and Arnebia euchroma from Huanglian Zicao Gel[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 35-38. DOI： 10.13422/j.cnki.syfjx.2012.15.023.

摘要

目的:优选黄连紫草膏中地黄、紫草的提取工艺。方法:以梓醇、毛蕊花糖苷、紫草素的含量和干膏得率为指标

考察乙醇体积分数、提取时间、乙醇用量、提取次数对提取工艺的影响

通过层次分析法确定各指标的权重系数

均匀设计优选醇提工艺。结果:最佳提取工艺为12倍量65%乙醇提取2 h。结论:该优选工艺稳定可行

可为提取工艺的确定和剂型改革提供依据。

Abstract

Objective:To optimize extraction technology of Rehmannia glutinosa and Arnebia euchroma from Huanglian Zicao gel.Method: With the content of the catalpol

verbascoside and shikonin

yield of dry extract as indexes

to investigate influence of ethanol concentration

extraction time

ethanol dosage and extraction times on extraction process

weight coefficient of indexes were determined by analytic hierarchy process

ethanol extraction technology was optimized by uniform design method.Result: The best extraction process was:extracted 2 h with 12 times the amount of 65% ethanol.Conclusion: This optimized technology was stable and feasible

it could provide basis for determination of extraction technology and formulations reformation.

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