WANG Hong-shan, LI Guo-hao, CAO Yi-min, et al. Montelukast Combined with Shegan Mahuang Tang for Treating of 86 Patients with Cough Variant Asthma[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 273-275.
WANG Hong-shan, LI Guo-hao, CAO Yi-min, et al. Montelukast Combined with Shegan Mahuang Tang for Treating of 86 Patients with Cough Variant Asthma[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(15): 273-275. DOI: 10.13422/j.cnki.syfjx.2012.15.080.
Objective: To study the clinical effect of montelukast combined with Shegan Mahuang Tang in treatment of cough variant asthma(CVA).Method:One hundred and seventy two patients with CVA were randomly divided into treatment group and control group
and the patients in control group were treated with salbutamol sulfate aerosol(1 dose per time
tid) combined with ketotifen(2 mg·d-1)
the patients in treatment group was received with montelukast(10 mg·d-1) combined with Shegan Mahuang Tang.In two groups the treatment lasted for two weeks.Forced expiratory volume 1(FEV1)
peak expiratory flow(PEF) and clinical symptom were measured
the clinical effect was compared.Result: The clinical symptom was changed by the teatments significantly.And the score in treatment group and control group was 1.1±0.2 and 1.8±0.3(P<0.05);the PEF changes of treatment group was 5.1%
it was lower than 9.2% in the control’s(P<0.05).The total effective rate of treatment group was 91.9%
and the rate of control group was 82.6%
(P<0.05).Conclusion: Shegan Mahuang Tang combined with montelukast shows satisfactory clinical efficacy in CVA