Objective: To observe Addie injection combined with radiotherapy and chemotherapy in the treatment of advanced lung cancer.Method: Agreed with the diagnosis standard

80 cases of esophageal cancer patients were randomly divided into observation group and control group

40 cases in each group.In the control group chemotherapy（DDP 25 mg·m-2d 1-3 PF scheme

5-FU 750 mg·m-2 d 1-5） was carried out for 2 weeks.In third week with TP regimen（TAX 135 mg·m-2 d 1

DDP 25 mg·m-2d 1-3） was given.At the same time using three-dimensional conformal radiotherapy

5 times/ week

for 2 consecutive weeks.The observation group at the start of therapy was given Addie injection intravenous drip

2 times a day.The 2 groups were treated for 4 weeks.Result: The comptete releasing rate in observation group was 52.50%

35% in control group

there was a significant difference;the total efficiency in treatment group was 95%

77.50% in control group

there was a significant difference（P<0.05）.For bone marrow toxicity reaction

peripheral neurotoxicity reaction

vomiting and other toxicities

the differences between the 2 groups were statistically significant（P<0.05）.Appetite

sleep

daily activity

state of mind

emotions

and interest in life

the 2 groups before and after treatment group there was a significant difference（P<0.05）.The treatment groups was better than the control gnoup（P<0.05）.In 2 groups of patients

the major adverse reactions to bone marrow depression and nausea

anorexia

in particular

rash

white blood cell

hemoglobin

thrombocytopenia and impairment of renal function had no significant difference.Conclusion: Addie injection combined with FP

TP sequential chemotherapy and radiotherapy for advanced lung cancer

the clinical curative effect is remarkable

can improve the quality of life.