Objective:To investigate effects of Juncus setchuensis decoction on the fasting blood glucose（FBG）and the fasting insulin levels（FINS） in rats.Method: The type 2 diabetes models in rats were made by fedding high lipids foods for one month together with injecting the streptozotocin（STZ）of small dose one time.The rats were randomly divided into 6 groups: control group

model group

metformin group（0.15 mg ·kg-1 · d-1）

Low

medium

and high dose groups of J.setchuensis decoction（2.5

5

10 g · kg-1 · d-1）.The contents of fasting blood glucose（FBG）

oral glucose tolerance test（OGTT） and fasting insulin（FINS） were determined.Result: FBG of diabetic rats which were fed with J.setchuensis decoction of medium and high dose respectively were（14.30±3.04）

（13.25±3.81）mmol · L-1

and glucose tolerance respectively were（13.44±3.24）

（13.03±4.72）mmol · L-1

and serum insulin levels were（15.40±3.76）

（16.39±4.75）mU · L-1.It showed that the J.setchuensis decoction in high dose and medium dose had significant effect of decreasing FBG and increasing FINS indiabetic rats.Conclusion: J.setchuensis decoction could decrease FBG and increase FINS levels in diabetic rats.