Objective:To study the pharmacodynamics on Fuyankang enema in treatment of chronic pelvic inflammatory disease

concerning anti-inflammatory

analgesic and immune.Method: Two hundred and forty Special-pathogen free KM rats were randomly divided into six groups: normal control group

western medicine group（Indomethacin 0.025 g · kg-1 · d-1）

high-dose Fuyankang ig group（2 g · kg-1 · d-1）

low-dose

middle-dose

and high-dose Fuyankang enema groups（2

1

0.5 g · kg-1 · d-1 respectively）.Effects of Fuyankang enema on abdominal capillary permeability

ear edema

hot-plate tests and writhing were observed.Other 120 rats were divided in the same way

but western medicine group was replaced by model group.Immune organ relative weight and the charcoal clearance index were also observed in prednisone acetate induced immunodepressive rats.Result: Fuyankang enema had inhibitory effects on mice ear edema（P<0.05 or P<0.01） and reduction of immune organ relative weight（P<0.05 or P<0.01） and charcoal clearance index（P<0.05） caused by prednisone had a reduction in ratio of writhing of mice（P<0.05） and had a addition on pain threshold of mouse（P<0.05）.Conclusion: Fuyankang enema has pharmaceutical effects in agreement with clinical effect on chronic pelvic inflammation

combination with oral medication is better.