Objective:To combine traditional Chinese and western medicine and western medical treatment of dermatomyositis clinical curative effect and the influence to tumor necrosis factor-α（TNF-α）to carry on the research analysis

confirmed by integrated traditional Chinese and western medicine therapy in the treatment of dermatomyositis in exact curative effect.Method: In 2008 August-2011 December in our hospital treatment of 78 cases of patients with dermatomyositis as the research object

divide them into two groups.A group of 52 patients

using a combination of traditional Chinese and western medicine therapy

observation group;a group of patients with 26 cases of using western medicine therapy

as compared to a control group.Treatment after a certain period

the clinical efficacy of the two groups and the influence to TNF-α were compared

and carries on statistics analysis.Result: Creatine phosphokinase（CPK） and erythrayte sedimentation rate（ESR） and adverse reaction of curative effect index all relatively contrast group have obvious advantages

through statistical analysis

with a significant difference（P<0.05） in TNF-α;comparison of the effect of observation group than in the control group

the patients have obvious advantages

through statistical analysis

with a significant difference（P<0.05）.Conclusion: In dermatomyositis therapy in combined treatment of TCM and western medicine than western medicine therapy has obvious curative effect

the influence to TNF-α and other advantages

is suitable for clinical use.