Objective:To study the clinical curative effect of Qinggan Jiangya drink（QJD） for early intervention of pre-hypertension and primary grade 1 hypertension.Method: One hundred and forty-six patients with hypertension and the primary grade 1 hypertension were randomly divided into treatment group and control group（n=73

each）

control group was in non drug intervention mode

the treatment group was given QJD 2

4

agent daily for 8 weeks.Blood pressure

blood lipids and scores of traditional Chinese medicine syndromes were observed before and after treatment.Result: Blood pressure after 4 and 8 weeks of treatment and that after another 4 weeks in treatment group was lower than those of the control group（P

<

0.01）.The recovery rate of blood pressure after treatment of 4 weeks and 8 weeks were 43.83% and 90.41% respectively

all was better than the control group（P

<

0.01）.The total effective rate of blood pressure in the treatment group was 95.89%

which is higher than that of 60.27% in control group（P

<

0.01）.After treatment

the total effective rate for the scores of syndromes was 98.63%

in the treatment group

while 56.16% in the controls（P

<

0.01）.The treatment also showed significant regulation for blood lipids.Conclusion: The clinical curative effect of early intervention for pre-hypertension and primary grade 1 hypertension by traditional Chinese medicine is promising.This is gained under the guidance of the principle of ’preventive intervention before a formed disease’.