Objective: To investigate the effect of Tanreqing injection in treatment of acute pneumonia (syndrome of phlegm-heat obstructing lung). Method: The acute pneumonia February were (syndrome of phlegm-heat obstructing lung) patients were randomly divided into study group and control group. Patients of two groups were given correct electrolyte disorders

sputum suction

antispasmodic asthma

leukotriene stabilizer

controling blood glucose

blood pressure

heart failure

lipid and other symptomatic treatment. Patients of the control group were given Shuanghuanglian injection 20 mL in 5% glucose injection 500 mL based on above conventional treatment

intravenous drip

one time per day. The treatment group was given Tanreqing injection 20 mL in 5% glucose injection 500 mL by intravenous drip based on above conventional treatment

one time per day. 2 weeks were as a course of treatment. Clinical efficacy and adverse reactions were compared between two groups. Result: 2 weeks after treatment

patients in the study group the total efficiency (90.63%) significantly higher than that in control group (68.75%)

and the difference was statistically significant (P<0.05). Heating time and eliminate time in the study group were significantly shorter than that in the control group [(41.35±21.32)h

(70.71±33.65)h] were significantly shorter than that in the control group[(50.85±28.33)h

(80.36±41.03)h]

and the difference was statistically significant (P<0.05). Patients in two groups during treatment had no hearing loss

acute kidney damage;there were 1 cases of treatment of electrocardiograph(ECG) after prolonged QT interval in patients of the study group

while patients in the control group without any adverse reactions

by statistical analysis of the incidence of adverse reaction in group with no significant difference compared to control group. Conclusion: Tanreqing injection in the treatment of acute pneumonia (syndrome of phlegm-heat obstructing lung) has clinical curative effect

less adverse reaction.