Objective:Under the same decoction conditions

to compare changes of contents of effective components and yield of dry extract between herbal pieces and decocting powders of Scutellariae Radix in decoction at different boiling times. Method:HPLC was used to determine contents of baicalin

wogonoside and baicalein with mobile phase of methanol-0.2% phosphoric acid(47:53) and detection wavelength at 280 nm.Taking yield of dry extract and contents of active ingredients as indexes

under the same conditions

decoction effect of herbal pieces and decocting powders of Scutellariae Radix at different decoction time was detected. Result:Decoction time of decocting powders of Scutellariae Radix were 10 min in the first and second time

while they were 30

10 min in herbal pieces.Contents of baicalin

wogonoside

baicalein and yield of dry extract in decocting powders were both greatly more than they were in herbal pieces of Scutellariae Radix. Conclusion:Decocting powders had advantages of time-saving and material-saving

this study could provide a reference for its application.