Objective:To observe the clinical efficacy in the deficiency of both Qi and Yin syndrome of type Ⅱ diabetes by using Shengmai powder combined Liuwei Dihuang pills. Method:Eighty patients were randomly divided into a treatment group (40 cases) and a control group (40 cases). Diabetes pills and insulin injection were used in both groups. But only give Shengmai powder combined Liuwei Dihuang pills to the treatment group. Then compare the clinical efficacy of two groups after a 4-week-course of treatment. Result:①Treatment group had significant differences in the improvement of the deficiency of both Qi and Yin syndrome compared with the control group (P<0.05). So treatment group was superior to the control group. ②The both groups patients' fasting blood glucose/postplandial 2 h blood sugar/glycated hemoglobin were all significantly decreased after the treatment

which had significantly differences compard with the prior treatment(P<0.05). However

there was no significance improvement comparison difference between the two groups. Conclusion:Conventional treatment combined Shengmai powder and Liuwei Dihuang pills has advantages in the amelioration of diabetics' characteristic of deficiency of both Qi and Yin syndrome such as hydrodipsia and desire for drinks

tired and debihtation

large food intake with rapid hungering

deficiency of Qi and disinclination to talk. So it is worth popularizing in clinical practice.