This paper aims to reveal the existing problems of the content determination of the stability study of traditional Chinese medicine(TCM) preparations and provide the reference for the quality control of the preparations

drug efficacy and the scientific stability study. Through searching the literature reports about the content determination of the stability study of TCM preparations since 2000

summarized the overview of stability of TCM preparations from the three aspects in the regulations of stability study

index component and the development trend of content determination method. And deeply analysis the existing problems of content determination of stability study

from the following three aspects: the index components selection

sample pretreatment and analytical methods

which can provide a reference for the stability study of TCM. At the same time

the editor noticed that R & D personnel focus on preparation process in the formulation standard preparation. In order to make the index components meet the standard

they make its enrichment by a variety of process and ignore the relationship between the index components and clinical effect

which greatly reduce the meaning of stability test. Therefore

in order to study on the effects material in TCM preparation

reduce the unsafe drug and improve study of content determination of stability study of TCM preparations

we need to absorb the advanced methods and techniques and carry out various aspects of theoretical study and experimental research on the basis of practice.