干燥对煮散颗粒粉体学特性的影响

梁少瑜; 曾永长; 朱咸阳; 汪涛; 仝小林; 向飞军

doi:10.13422/j.cnki.syfjx.2014130038

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干燥对煮散颗粒粉体学特性的影响

工艺与制剂 | 更新时间：2024-01-04

- 干燥对煮散颗粒粉体学特性的影响
- Effect of Drying on Micromeritic Properties of Boiling Powder Granules
- 中国实验方剂学杂志 2014年20卷第13期页码：38-40
- 作者机构：
- 作者简介：
- 基金信息：
  
  北京市科学技术委员会“十病十药”研发项目（Z121102001112010）
- DOI：10.13422/j.cnki.syfjx.2014130038
  中图分类号： R283.6
- 纸质出版日期：2014
- 稿件说明：
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梁少瑜, 曾永长, 朱咸阳, 等. 干燥对煮散颗粒粉体学特性的影响[J]. 中国实验方剂学杂志, 2014,20(13):38-40.

LIANG Shao-yu, ZENG Yong-chang, ZHU Xian-yang, et al. Effect of Drying on Micromeritic Properties of Boiling Powder Granules[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(13): 38-40.
梁少瑜, 曾永长, 朱咸阳, 等. 干燥对煮散颗粒粉体学特性的影响[J]. 中国实验方剂学杂志, 2014,20(13):38-40. DOI： 10.13422/j.cnki.syfjx.2014130038.

LIANG Shao-yu, ZENG Yong-chang, ZHU Xian-yang, et al. Effect of Drying on Micromeritic Properties of Boiling Powder Granules[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(13): 38-40. DOI： 10.13422/j.cnki.syfjx.2014130038.

摘要

目的：考察药材含水量对煮散颗粒粉体学特性的影响。方法：采用筛分法测定煮散颗粒的粒径分布，量筒法测定堆积密度和振实密度，固定漏斗法测定休止角，观察外观性状，考察含水量对煮散颗粒的粉体学特性的影响。结果：采用低温干燥法，设定干燥温度60 ℃。当干姜、炙甘草、火单苦杏仁、水蛭含水量依次控制约11%，8%，12%，5%时，制备的煮散颗粒粒径分布、流动性及外观性状均较好。结论：中药饮片含水量对煮散颗粒的粉体学特性参数具有重要影响，适度干燥处理有助于制备粉体学特性较好的煮散颗粒。

Abstract

Objective: To investigate effect of moisture content on micromeritic properties of boiling powder granules. Method: Particle size distribution of boiling powder granules was determined by screening method

bulk desity and tap density were measured by graduated cylinder assay

angle of repose was determined by fixed-funnel method

then observed grinding characteristics by microscope

effect of moisture content on micromeritic properties of boiling powder granules was investigated. Result: Low temperature drying was adopted with temperature at 60 ℃.When moisture contents of Zingiberis Rhizoma

Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle

Armeniacae Semen Amarum and Hirudo controlled about 11%

12% and 5%

respectively

these prepared boiling powder granules had good particle size distribution

mobility and appearance characters. Conclusion: Moderate drying helped to prepare boiling powder granules with good micromeritic properties.

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