Objective: To study the chemical constituents of the leaf of Liquidambar formosana. Method: The chemical constituents were isolated by column chromatography on silica gel

Sephadex LH-20 and MPLC. Their chemical structures were elucidated on the basis of special analysis. Result: Nine compounds were isolated from ethyl acetate position

whose structures were elucidated as (+)-lyoniresinol-3α-O-β-D-glucopyranoside (1)

(6R

7S

8S)-7a-[(β-glucopyranosyl)oxy]lyoniresinol (2)

(+)-5' methoxyisolariciresinol 3α-O-β-D-glucopyranoside (3)

(-)-isolariciresinol 3α-O-β-D-glucopyranoside (4)

(3S

5R

6R

7E

9S)-megastigman-7-ene-3

5

6

9-tetrol (5)

kaempferol-4'-O-β-D-glucopyranoside (6)

kaempferol-4'-O-α-L-rhamonpyranoyl-β-D-glucopyranoside (7)

kaempferol-3-O-β-D-(6"-galloyl) galactopyranoside (8)

quercetin-3-O-β-D-(6"-galloyl) galactopyranoside (9). Conclusion: Compounds 1-9 were isolated from this plant for the first time.