Objective: To explore clinical efficacy and security of the 4th prescription of cervical spondylosis disease combined with acupotomology on vertebral artery type of cervical spondylosis. Method: Sixty patients with vertebral artery type of cervical spondylosis were chosen in recent years in our hospital and randomly divided into two groups including control group (30 patients) with electric acupuncture combined with massage and observation group (30 patients) with the 4th prescription of cervical spondylosis disease combined with acupotomology;and the clinical improving efficacy

clinical signs and symptoms scores and adverse effects occurrence of both groups were compared. Result: The clinical improving efficacy of observation group was significant higher than control group(P<0.05). The clinical signs and symptoms scores of both groups after treatment was significant better than before treatment

and the improving degree of observation group was significant better than control group(P<0.05). There was no significant difference in subcutaneous haematomas incidence between 2 groups. Conclusion: Compared with electric acupuncture combined with massage treatment

the 4th prescription of cervical spondylosis disease combined with acupotomology on vertebral artery type of cervical spondylosis can efficiently improve clinical signs and symptoms scores

higher life quality and do not increase the risk of adverse effects.