Objective: Discuss intervention effect of Shuxue Tong injection to patients' blood lipid in treating acute cerebral infarction and influence to serum high sensitivity C-reactive protein(hs-CRP)

adiponectin(APN)

oxidized low-density lipoprotein(ox-LDL) and tumor necrosis factor-α(TNF-α). Method: Sixty-seven patients were randomly divided into control group (22 cases) and observation group (45 cases)by random number table.Patients in the control group received conventional western medicine treatment

and atorvastatin calcium tablets were used as medicine of reducing lipid

10 mg/time

1 time/day

taken orally after dinner.Based on the treatment of control group

patients in the observation group added Shuxue Tong injection

6 mL/time

intravenous infusion

1 time/day

course of treatment were 14 days.On day 0 and at the seventh and fourteenth day after treatment

severity of neurological impairment was evaluated by National Institute of Health Stroke Scale(NIHSS) scale.Triglyceride(TG)

level of total cholesterol(TC)

high-density lipoprotein(HDL-C) and low density lipoprotein(LDL-C) were detected.hs-CRP was detected by enzyme linked immunosorbent assay.APN

ox-LDL and TNF-α were detected.Before and after treatment

hemorheology was detected. Result: At the seventh day after treatment

compared with the time before treatment

scores of NIHSS in two groups decreased(P<0.01)

which meant no statistical significance from the differences between two groups.At the fourteenth day after treatment

scores of NIHSS in two groups kept decreasing(P<0.01)

and score of NIHSS in observation group was lower than in control group(P<0.01).Compared with the time before treatment

levels of serum hs-CRP

ox-LDL and TNF-α decreased(P<0.01)

and which in observation group were lower than those in control group(P<0.01).Compared with the time before treatment

levels of serum APN in two groups increased(P<0.01)

and which in observation group was higher than in control group(P<0.01).Levels of TC

TG and LDL-C in two groups decreased obviously(P<0.01)

and levels of TC and TG in observation group were lower than those in control group(P<0.01).Levels of HDL-C in two groups increased(P<0.01)

and there was no statistical significance from the differences between two groups.Amelioration of whole blood viscosity

aggregation rate of platelet

plasma viscosity and hematokrit in observation group was superior to those in control group(P<0.01). Conclusion: Shuxue Tong injection can ameliorate patients' neurological function in treating acute cerebral infarction and patients' lipid metabolism

and it has functions of anti-inflammatory

antioxidant and ameliorating cerebral microcirculation.