Objective: To observer the curative effect of Tongfu Yunchang decoction to treat adhesion sex intestinal obstruction by taken orally and enema remedy and protection mechanism to intestinal barrier function. Method: Ninety-two patients were randomly divided into control group (46 cases) and observation group (46 cases) according to digital method.Both groups received conventional western medicine treatment.Patients in control group received fasting

continuous gastrointestinal decompression

rehydration

balance acid-base and water electrolyte disorder.Control group patients took cefotaxime sodium

4 g/time

intravenous drip

2 does/day

octreotide

0.1 mg/time

subcutaneous injectionm

3 times/day.Based on the treatment of control group

patients in observation group added Tongfu Yunchang decoction by taken orally and enema remedy

1 does/day.One treatment course for five days and they could received 2 continuous treatment courses.Closely observe patients' condition change to decide to use surgery or not during the treatment.Record exhaust time

defecation time

gastric tube indwelling time

recovery time

hospital stay-time and transit mode for two groups.Record the main signs and symptoms score before the treatment and at the fifth day during cure.Record the level of serum interleukin-6 (IL-6)

tumor necrosis factor-α (TNF-α)

diamine oxidase (DAO) and malonic acid (MDA) at the fifth day during treatment. Result: The total effective rate in observation group was 89.13% superior to 71.74% in control group(P<0.05).The exsufflation time

defecating time

indwelling time of gastric

delayed restoration of gastrointestinal function and length of stay in observation group were all shorter than those in control group(P<0.01).Operating conversive rate in observation group was 28.26% lower than 10.87% in control group(P<0.05).After five days of treatment

scores of abdominal distension and pain

nausea and vomit

fever

gurgling sound and exsufflation in observation group were all less than those in control group(P<0.01).Levels of IL-6

TNF-α

DAO and MDA in observation group were all less than those in control group(P<0.01). Conclusion: Based on the treatment of conventional western medicine

Tongfu Yunchang decoction combined with clysis can ameliorate clinical symptoms of adhesive intestinal obstruction

accelerate recovery of intestinal function and reduce operating conversive rate

there was a significant curative efficacy. And it can also reduce levels of IL-6

TNF-α

DAO and MDA.