Objective: To evaluate systematically the clinical efficacy and safety of Danhong injection for the treatment of stable angina pectoris. Method: Randomized controlled trials (RCTs) about Danhong injection for stable angina pectoris were searched systemically and comprehensively. Two reviewers assessed the quality of the included studies by the Cochrane risk of bias

and extracted the information. Meta-analysis was conducted with the software Review Manager 5.2. Result: A total of 9 studies with 596 participants were included

and the quality of the studies was relatively low. There was one study divided into groups by the order of seeking medical advice

one study used the double-blinding method

one study may have 2 patients dropped

and the others mentioned random only. In the meta-analysis

the results of Danhong group were significantly superior to the west conventional therapy group in increasing the total effective rate [RR=1.30

95%CI(1.21

1.41)

P<0.000 01]

reducing the frequency of angina pectoris

and improving the herorheology index.There were 5 authors explained none adverse drug reactions (ADR) reported in their studies

and 2 studies reported 6 cases of ADRs

none series ADR occurrence. Conclusion: Comparing with the conventional therapy of the control group used for treating stable angina pectoris

Danhong injection combined with the conventional therapy was relatively effective and safety

which was based on the systematic review.