Objective: To dicuss synergism and attenuation of Fuzheng Kanglao decoction assisted chemotherapy for initial treatment of secondary pulmonary tuberculosis and observe its adjust function to cellular immunity. Method: Two hundred and twenty-six cases were randomly divided into control group(112 cases) and observation group(114 cases) by digital method.Patients in the control group received isoniazide with 0.3 g/time and 1 time/day

rifampicin with 0.45-0.6 g/time

taken on an empty stomach

pyrazinamide with 1.5 g/time and 1 time/d

ethambutol with 0.75-1.0 g/time and 1 time/d.Based on treatment of the control group

patients in the observation group added Fuzheng Kanglao decoction with 1 dose/day.Course of treatment in those two groups were both 1 months.Sputum bacteria and liver function were detected every month.Before treatment and at the second

fourth and sixth months

scores of main symptoms and signs in the observation group were evaluated.Before and after treatment

T-lymphocyte subpopulation of peripheral blood detected by flow cytometry and quality of life also was detected. Result: Cure rate in the observation group was 85.96% superior to 73.77% in the control group(P<0.05).Pulmonary shadows absorption in the observation group was 77.19% superior to 65.18% in the control group(P<0.05).At the second

forth and sixth months after treatment

scores of main symptoms and signs in the observation group were lower than those in the control group(P<0.01).After treatment

dimension scores of physiology

mentality

social relations

subjective feeling of quality of life and state of health increased(P<0.01)

and which in the observation group were higher than those in the control group(P<0.01)

CD3+

CD4+ and CD4+/CD8+ in the observation group were higher than those in the control group

but CD8+ was lower than in the control group(P<0.01).Occurrence rate of abnormal liver function in the observation group was 9.6% lower than 20.5% in the control group(P<0.05). Conclusion: Fuzheng Kanglao decoction assisted chemotherapy had function of synergism and attenuation for initial treatment of secondary pulmonary tuberculosis

and it could improve patients' quality of life.Fuzheng Kanglao decoction could adjust function of patients' cellular immunity and contribute bodies to coping with scavenging action of germ.