Objective: Evaluate the efficacy and safety of acupuncture combined with Chinese medicine on patients with vascular cognitive impairment no dementia from cognitive function

activities of daily living and syndromes of traditional Chinese medicine. Method: This is a randomized

active-controlled and open-label trial. In total

eighty patients with vascular cognitive impairment no dementia were enrolled and divided evenly into control and trial groups. Based on the foundation treatment of vascular risk factors

the tail group was given Fuzhi capsule combined with acupuncture

and the control group was given oxiracetam capsules. The mini-mental state examination (MMSE)

montreal cognitive assessment(MOCA)

activities of daily living(ADL)

syndrome differentiation scale of vascular dementia(SDSVD) scores will be observed after a 12-week treatment period. Result: The MMSE and MOCA scores of each group of was increased after the treatment. Compared with the control group

the MMSE and MOCA scores of the trial group increased obviously

the difference was statistically significant (P<0.05). The ADL and SDSVD scores were reduced after the treatment. Compared with the control group

the ADL and SDSVD scores of the trial group reduced obviously

the difference was statistically significant (P<0.05). Conclusion: Combineing with acupuncture and Chinese medicine has beneficial effects on patients with vascular cognitive impairment no dementia. It can improve the cognitive function and activities of daily living significantly. The results of this study will provide evidence for developing a comprehensive therapy regimen

which can delay the progress of dementia and improve the quality of life for VCIND patients.