Objective: To analyze composition principles of the prescriptions in the book of〈The Prescription of Traditional Chinese Medicine(TCM)Dictionary〉for the treatment of complex symptoms of adverse rising of gastric Qi of deficiency of spleen. Method: The prescriptions for complex symptoms of adverse rising of gastric qi of deficiency of spleen were collected

sorted and entered into the TCM inheritance system (V1.3) to analyze the composition principles by the methods of entropy and apriori. Result: Based on the analysis of 1 452 cases of prescriptions which have 934 medications

there were 45 medications with more than 50 frequencies are mined from the database.Composition principles were obtained with apriori method:there were 29 frequently used herbal pair with more than 100 frequencies(support≤20)

34 core combinations with more than 60 frequencies(support≤20).The association principles for those medications in the prescriptions were analyzed(support≤20

confidence≤0.9).Principles were obtained with entropy:there were 29 core combinations which would compose the new prescriptions

and 29 new prescriptions were found by hierarchical clustering method.There were 12 prescriptions matching with Sijunzi tang(semblance=0.5). Conclusion: We should chose strengthening spleen and benefiting vital medications primarily

assisting with regulating stomach and calming the adverse-rising gastric Qi

to treat the complex symptoms of adverse rising of gastric Qi of deficiency of spleen.