The review outline Aconiti Lateralis Radix Praeparata processing technology in present and inspection standards respectively and analysis Aconiti Lateralis Radix Praeparata processing mechanism thoroughly. Aconiti Lateralis Radix Praeparata is used widely in traditional Chinese medicine to treat various disease mainly about the cardiovascular system. Processing and toxicology reduction of Aconiti Lateralis Radix Praeparata is very important because of its large toxicology

Because of its severe toxicity can cause death. The method of fuzi processing originated from ancient time and there are many new processing methods appeared. However

there has been no measure standard. Aconitine limited method was used to examine processing in ‘Chinese pharmacopoeia’. The toxicity of fuzi decreased after processing. Processed aconite

heishunpian

white monkshood can be directly used as medicine. The mechanism of Aconiti Lateralis Radix Praeparata processing attenuated its toxicity is mainly that various types of alkaloids were destroyed and loss in the processing. Toxic diester aconitum hydrolysis into benzoyl ester type alkaloids

then hydrolyzed hydrolysis into alcohol amine aconine alkaloids. Although our objective is to reduce the toxicity of Aconite Lateralis Radix Praeparata

the content of effective components should also be taken consideration. It is still difficult to decrease toxicity and keep effective functions at the same time. Changes in chemical composition during processing is important to study the mechanism of aconite processing. This paper summarize the processing methods of Aconiti Lateralis Radix Praeparata and the mechanism of toxicology reduction

which can serve as a reference for study on Aconiti Lateralis Radix Praeparata processing and clinical using.