WANG Rui, XINOG Ru-qin, LUO Jia-gang, et al. Effect on Anti-tyrosinase and Antioxidation Activities of Extract from [J]. Chinese journal of experimental traditional medical formulae, 2014, 20(18): 70-72.
WANG Rui, XINOG Ru-qin, LUO Jia-gang, et al. Effect on Anti-tyrosinase and Antioxidation Activities of Extract from [J]. Chinese journal of experimental traditional medical formulae, 2014, 20(18): 70-72. DOI: 10.13422/j.cnki.syfjx.2014180070.
Objective: To study anti-tyrosinase and antioxidation activities of extract from Oroxylum indicum. Method: This paper took different polar fractions of extract from the O. indicum ethanolic extract as research objects
measured its inhibition of tyrosinase and 1
1-diphenyl-2-picrylhydrazyl free radical(DPPH·) and the hydroxyl free radical (·OH) scavenging ability. Result: Its alcohol extract of ethyl acetate extract (EAO)
n-butanol extract (n-BO) and water extract (WO) had inhibition to tyrosinaes
the values of IC50 reached 3.081 4
8.525 3
22.750 8 g·L-1 respectively;EAO
n-BO
WO had stonger scavenging effect of DPPH·and·OH
the order of scavenging ability was EAO>n-BO>WO. Conclusion: O. indicum. had better tyrosinase inhibitory and antioxidation
its antioxidation ability had positive correlation with its anti-tyrosinase. Its functional components were mainly distributed in the ethyl acetate phase.